Molecola del Mese
di David S. Goodsell
e Mauro Tonellato
Ribonucleasi A
Indice 2008

 PianetaChimica

Structure ID 
Title 
Authors 
Publication Year 
Journal Name 
Volume ID  First Page  PubMed 
11BA Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2',5')adenosine. Vitagliano, L., Adinolfi, S., Riccio, A., Sica, F., Zagari, A., Mazzarella, L. 1998 Protein Sci. 7 1691 10082366
11BG A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease. Vitagliano, L., Adinolfi, S., Sica, F., Merlino, A., Zagari, A., Mazzarella, L. 1999 J.Mol.Biol. 293 569 10543951
1A2W The crystal structure of a 3D domain-swapped dimer of RNase A at a 2.1-A resolution. Liu, Y., Hart, P.J., Schlunegger, M.P., Eisenberg, D. 1998 Proc.Natl.Acad.Sci.USA 95 3437 9520384
1A4Y Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution. Papageorgiou, A.C., Shapiro, R., Acharya, K.R. 1997 EMBO J. 16 5162 9311977
1A5P Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A. Pearson, M.A., Karplus, P.A., Dodge, R.W., Laity, J.H., Scheraga, H.A. 1998 Protein Sci. 7 1255 9605332
1A5Q Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A. Pearson, M.A., Karplus, P.A., Dodge, R.W., Laity, J.H., Scheraga, H.A. 1998 Protein Sci. 7 1255 9605332
1AFK Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution. Leonidas, D.D., Shapiro, R., Irons, L.I., Russo, N., Acharya, K.R. 1997 Biochemistry 36 5578 9154942
1AFL Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution. Leonidas, D.D., Shapiro, R., Irons, L.I., Russo, N., Acharya, K.R. 1997 Biochemistry 36 5578 9154942
1AFU Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution. Leonidas, D.D., Shapiro, R., Irons, L.I., Russo, N., Acharya, K.R. 1997 Biochemistry 36 5578 9154942
1AGI Crystal structure of bovine angiogenin at 1.5-A resolution. Acharya, K.R., Shapiro, R., Riordan, J.F., Vallee, B.L. 1995 Proc.Natl.Acad.Sci.USA 92 2949 7708754
1ANG Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease. Acharya, K.R., Shapiro, R., Allen, S.C., Riordan, J.F., Vallee, B.L. 1994 Proc.Natl.Acad.Sci.USA 91 2915 8159679
1AQP Crystal structures of the copper and nickel complexes of RNase A: metal-induced interprotein interactions and identification of a novel copper binding motif. Balakrishnan, R., Ramasubbu, N., Varughese, K.I., Parthasarathy, R. 1997 Proc.Natl.Acad.Sci.USA 94 9620 9275172
1AWZ Three-dimensional solution structure of human angiogenin determined by 1H,15N-NMR spectroscopy--characterization of histidine protonation states and pKa values. Lequin, O., Thuring, H., Robin, M., Lallemand, J.Y. 1997 Eur.J.Biochem. 250 712 9461294
1B1E Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. Leonidas, D.D., Shapiro, R., Allen, S.C., Subbarao, G.V., Veluraja, K., Acharya, K.R. 1999 J.Mol.Biol. 285 1209 9918722
1B1I Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. Leonidas, D.D., Shapiro, R., Allen, S.C., Subbarao, G.V., Veluraja, K., Acharya, K.R. 1999 J.Mol.Biol. 285 1209 9918722
1B1J Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. Leonidas, D.D., Shapiro, R., Allen, S.C., Subbarao, G.V., Veluraja, K., Acharya, K.R. 1999 J.Mol.Biol. 285 1209 9918722
1B6V Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution. Vatzaki, E.H., Allen, S.C., Leonidas, D.D., Trautwein-Fritz, K., Stackhouse, J., Benner, S.A., Acharya, K.R. 1999 Eur.J.Biochem. 260 176 10091597
1BAF 2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten. Brunger, A.T., Leahy, D.J., Hynes, T.R., Fox, R.O. 1991 J.Mol.Biol. 221 239 1920408
1BC4 The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana (bullfrog). Chang, C.F., Chen, C., Chen, Y.C., Hom, K., Huang, R.F., Huang, T.H. 1998 J.Mol.Biol. 283 231 9761686
1BEL Structure of crystal form IX of bovine pancreatic ribonuclease A. Dung, M.H., Bell, J.A. 1997 Acta Crystallogr.,Sect.D 53 419 15299907
1BSR Bovine seminal ribonuclease: structure at 1.9 A resolution. Mazzarella, L., Capasso, S., Demasi, D., Di Lorenzo, G., Mattia, C.A., Zagari, A. 1993 Acta Crystallogr.,Sect.D 49 389 15299514
1BZQ A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops. Decanniere, K., Desmyter, A., Lauwereys, M., Ghahroudi, M.A., Muyldermans, S., Wyns, L. 1999 Structure Fold.Des. 7 361 10196124
1C0B X-ray crystal structures of a severely desiccated protein Bell, J.A. 1999 Protein Sci. 8 2033 10548049
1C0C X-ray crystal structures of a severely desiccated protein Bell, J.A. 1999 Protein Sci. 8 2033 10548049
1C8W Excavating an active site: the nucleobase specificity of ribonuclease A. Kelemen, B.R., Schultz, L.W., Sweeney, R.Y., Raines, R.T. 2000 Biochemistry 39 14487 11087402
1C9V Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding. Park, C., Schultz, L.W., Raines, R.T. 2001 Biochemistry 40 4949 11305910
1C9X Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding. Park, C., Schultz, L.W., Raines, R.T. 2001 Biochemistry 40 4949 11305910
1CJQ X-ray crystallographic studies of the denaturation of ribonuclease S. Ratnaparkhi, G.S., Varadarajan, R. 1999 Proteins 36 282 10409822
1CJR X-ray crystallographic studies of the denaturation of ribonuclease S. Ratnaparkhi, G.S., Varadarajan, R. 1999 Proteins 36 282 10409822
1D5D Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics. Ratnaparkhi, G.S., Varadarajan, R. 2000 Biochemistry 39 12365 11015216
1D5E Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics. Ratnaparkhi, G.S., Varadarajan, R. 2000 Biochemistry 39 12365 11015216
1D5H Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics. Ratnaparkhi, G.S., Varadarajan, R. 2000 Biochemistry 39 12365 11015216
1DFJ A structural basis of the interactions between leucine-rich repeats and protein ligands. Kobe, B., Deisenhofer, J. 1995 Nature 374 183 7877692
1DY5 The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: hydration and sterochemical analysis. Esposito, L., Vitagliano, L., Sica, F., Sorrentino, G., Zagari, A., Mazzarella, L. 2000 J.Mol.Biol. 297 713 10731423
1DYT Three-dimensional crystal structure of human eosinophil cationic protein (RNase 3) at 1.75 A resolution. Mallorqui-Fernandez, G., Pous, J., Peracaula, R., Aymami, J., Maeda, T., Tada, H., Yamada, H., Seno, M., de Llorens, R., Gomis-Ruth, F.X., Coll, M. 2000 J.Mol.Biol. 300 1297 10903870
1DZA Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the design of cytotoxic ribonucleases. Pous, J., Canals, A., Terzyan, S.S., Guasch, A., Benito, A., Ribo, M., Vilanova, M., Coll, M. 2000 J.Mol.Biol. 303 49 11021969
1E1H Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity. Segelke, B., Knapp, M., Kadkhodayan, S., Balhorn, R., Rupp, B. 2004 Proc.Natl.Acad.Sci.Usa 101 6888 15107500
1E21 Three-dimensional structure of human RNase 1 delta N7 at 1.9 A resolution Pous, J., Mallorqui-Fernandez, G., Peracaula, R., Terzyan, S.S., Futami, J., Tada, H., Yamada, H., Seno, M., de Llorens, R., Gomis-Ruth, F.X., Coll, M. 2001 Acta Crystallogr., Sect.D 57 498 11264578
1E6J Mutual conformational adaptations in antigen and antibody upon complex formation between an Fab and HIV-1 capsid protein p24. Monaco-Malbet, S., Berthet-Colominas, C., Novelli, A., Battai, N., Piga, N., Cheynet, V., Mallet, F., Cusack, S. 2000 Structure 8 1069 11080628
1E6O Mutual conformational adaptations in antigen and antibody upon complex formation between an Fab and HIV-1 capsid protein p24. Monaco-Malbet, S., Berthet-Colominas, C., Novelli, A., Battai, N., Piga, N., Cheynet, V., Mallet, F., Cusack, S. 2000 Structure Fold.Des. 8 1069 11080628
1EIC Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution. Chatani, E., Hayashi, R., Moriyama, H., Ueki, T. 2002 Protein Sci. 11 72 11742124
1EID Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution. Chatani, E., Hayashi, R., Moriyama, H., Ueki, T. 2002 Protein Sci. 11 72 11742124
1EIE Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution. Chatani, E., Hayashi, R., Moriyama, H., Ueki, T. 2002 Protein Sci. 11 72 11742124
1EOS Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2',5')guanosine. Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L. 2000 Protein Sci. 9 1217 10892814
1EOW Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2',5')guanosine. Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L. 2000 Protein Sci. 9 1217 10892814
1F0V A domain-swapped RNase A dimer with implications for amyloid formation Liu, Y.S., Gotte, G., Libonati, M., Eisenberg, D.S. 2001 Nat.Struct.Biol. 8 211 11224563
1F58 Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Stanfield, R., Cabezas, E., Satterthwait, A., Stura, E., Profy, A., Wilson, I. 1999 Structure Fold.Des. 7 131 10368281
1FEV Structural and thermodynamic consequences of introducing alpha-aminoisobutyric acid in the S peptide of ribonuclease S. Ratnaparkhi, G.S., Awasthi, S.K., Rani, P., Balaram, P., Varadarajan, R. 2000 Protein Eng. 13 697 11112508
1FS3 Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution. Chatani, E., Hayashi, R., Moriyama, H., Ueki, T. 2002 Protein Sci. 11 72 11742124
1GIO Solution structure of bovine angiogenin by 1H nuclear magnetic resonance spectroscopy. Lequin, O., Albaret, C., Bontems, F., Spik, G., Lallemand, J.Y. 1996 Biochemistry 35 8870 8688423
1GPO The rational construction of an antibody against cystatin: lessons from the crystal structure of an artificial Fab fragment. Schiweck, W., Skerra, A. 1997 J.Mol.Biol. 268 934 9180382
1GQV Atomic Resolution (0.98 A) Structure of Eosinophil-Derived Neurotoxin Swaminathan, G.J., Holloway, D.E., Veluraja, K., Acharya, K.R. 2002 Biochemistry 41 3341 11876642
1GV4 The crystal structure of the mouse apoptosis-inducing factor AIF. Mate, M.J., Ortiz-Lombardia, M., Boitel, B., Haouz, A., Tello, D., Susin, S.A., Penninger, J., Kroemer, G., Alzari, P.M. 2002 Nat.Struct.Biol. 9 442 11967568
1GV7 Guest-host crosstalk in an angiogenin-RNase A chimeric protein. Holloway, D.E., Shapiro, R., Hares, M.C., Leonidas, D.D., Acharya, K.R. 2002 Biochemistry 41 10482 12173935
1H0D The crystal structure of human angiogenin in complex with an antitumor neutralizing antibody. Chavali, G.B., Papageorgiou, A.C., Olson, K.A., Fett, J.W., Hu, G., Shapiro, R., Acharya, K.R. 2003 Structure 11 875 12842050
1H1H The crystal structure of eosinophil cationic protein in complex with 2',5'-ADP at 2.0 A resolution reveals the details of the ribonucleolytic active site. Mohan, C.G., Boix, E., Evans, H.R., Nikolovski, Z., Nogues, M.V., Cuchillo, C.M., Acharya, K.R. 2002 Biochemistry 41 12100 12356310
1H52 Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography. Leonidas, D.D., Chavali, G.B., Jardine, A.M., Li, S., Shapiro, R., Acharya, K.R. 2001 Protein Sci. 10 1669 11468363
1H53 Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography. Leonidas, D.D., Chavali, G.B., Jardine, A.M., Li, S., Shapiro, R., Acharya, K.R. 2001 Protein Sci. 10 1669 11468363
1H8X The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization. Canals, A., Pous, J., Guasch, A., Benito, A., Ribo, M., Vilanova, M., Coll, M. 2001 Structure 9 967 11591351
1HBY Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography. Leonidas, D.D., Chavali, G.B., Jardine, A.M., Li, S., Shapiro, R., Acharya, K.R. 2001 Protein Sci. 10 1669 11468363
1HI2 Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R. 2001 J.Biol.Chem. 276 15009 11154698
1HI3 Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R. 2001 J.Biol.Chem. 276 15009 11154698
1HI4 Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R. 2001 J.Biol.Chem. 276 15009 11154698
1HI5 Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R. 2001 J.Biol.Chem. 276 15009 11154698
1IGY Crystallographic structure of an intact IgG1 monoclonal antibody. Harris, L.J., Skaletsky, E., McPherson, A. 1998 J.Mol.Biol. 275 861 9480774
1IK6 3D structure and significance of the GPhiXXG helix packing motif in tetramers of the E1beta subunit of pyruvate dehydrogenase from the archeon Pyrobaculum aerophilum. Kleiger, G., Perry, J., Eisenberg, D. 2001 Biochemistry 40 14484 11724561
1IQW Crystal structure of the antigen-binding fragment of apoptosis-inducing mouse anti-human Fas monoclonal antibody HFE7A. Ito, S., Takayama, T., Hanzawa, H., Ichikawa, K., Ohsumi, J., Serizawa, N., Hata, T., Haruyama, H. 2002 J.Biochem.(Tokyo) 131 137 11754745
1IZP Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Kadonosono, T., Chatani, E., Hayashi, R., Moriyama, H., Ueki, T. 2003 Biochemistry 42 10651 12962489
1IZQ Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Kadonosono, T., Chatani, E., Hayashi, R., Moriyama, H., Ueki, T. 2003 Biochemistry 42 10651 12962489
1IZR Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Kadonosono, T., Chatani, E., Hayashi, R., Moriyama, H., Ueki, T. 2003 Biochemistry 42 10651 12962489
1J7Z Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. Ratnaparkhi, G.S., Varadarajan, R. 2001 J.Biol.Chem. 276 28789 11373282
1J80 Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. Ratnaparkhi, G.S., Varadarajan, R. 2001 J.Biol.Chem. 276 28789 11373282
1J81 Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. Ratnaparkhi, G.S., Varadarajan, R. 2001 J.Biol.Chem. 276 28789 11373282
1J82 Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. Ratnaparkhi, G.S., Varadarajan, R. 2001 J.Biol.Chem. 276 28789 11373282
1JN4 Cleavage of 3',5'-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin Jardine, A.M., Leonidas, D.D., Jenkins, J.L., Park, C., Raines, R.T., Acharya, K.R., Shapiro, R. 2001 Biochemistry 40 10262 11513604
1JRH Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex. Sogabe, S., Stuart, F., Henke, C., Bridges, A., Williams, G., Birch, A., Winkler, F.K., Robinson, J.A. 1997 J.Mol.Biol. 273 882 9367779
1JS0 Structures of the two 3D domain-swapped RNase A trimers. Liu, Y., Gotte, G., Libonati, M., Eisenberg, D. 2002 Protein Sci. 11 371 11790847
1JVT Reversible Substrate-Induced Domain Motions in Ribonuclease A Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L. 2002 Proteins 46 97 11746706
1JVU Reversible Substrate-Induced Domain Motions in Ribonuclease A Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L. 2002 Proteins 46 97 11746706
1JVV Reversible Substrate-Induced Domain Motions in Ribonuclease A Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L. 2002 Proteins 46 97 11746706
1K2A Crystallographic and functional studies of a modified form of eosinophil-derived neurotoxin (EDN) with novel biological activities. Chang, C., Newton, D.L., Rybak, S.M., Wlodawer, A. 2002 J.Mol.Biol. 317 119 11916383
1K4C Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Zhou, Y., Morais-Cabral, J.H., Kaufman, A., MacKinnon, R. 2001 Nature 414 43 11689936
1K4D Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Zhou, Y., Morais-Cabral, J.H., Kaufman, A., MacKinnon, R. 2001 Nature 414 43 11689936
1K58 Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R. 2002 Biochemistry 41 2552 11851402
1K59 Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R. 2002 Biochemistry 41 2552 11851402
1K5A Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R. 2002 Biochemistry 41 2552 11851402
1K5B Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R. 2002 Biochemistry 41 2552 11851402
1KF2 Atomic resolution structures of ribonuclease A at six pH values. Berisio, R., Sica, F., Lamzin, V.S., Wilson, K.S., Zagari, A., Mazzarella, L. 2002 Acta Crystallogr.,Sect.D 58 441 11856829
1KF3 Atomic resolution structures of ribonuclease A at six pH values. Berisio, R., Sica, F., Lamzin, V.S., Wilson, K.S., Zagari, A., Mazzarella, L. 2002 Acta Crystallogr.,Sect.D 58 441 11856829
1KF4 Atomic resolution structures of ribonuclease A at six pH values. Berisio, R., Sica, F., Lamzin, V.S., Wilson, K.S., Zagari, A., Mazzarella, L. 2002 Acta Crystallogr.,Sect.D 58 441 11856829
1KF5 Atomic resolution structures of ribonuclease A at six pH values. Berisio, R., Sica, F., Lamzin, V.S., Wilson, K.S., Zagari, A., Mazzarella, L. 2002 Acta Crystallogr.,Sect.D 58 441 11856829
1KF7 Atomic resolution structures of ribonuclease A at six pH values. Berisio, R., Sica, F., Lamzin, V.S., Wilson, K.S., Zagari, A., Mazzarella, L. 2002 Acta Crystallogr.,Sect.D 58 441 11856829
1KF8 Atomic resolution structures of ribonuclease A at six pH values. Berisio, R., Sica, F., Lamzin, V.S., Wilson, K.S., Zagari, A., Mazzarella, L. 2002 Acta Crystallogr.,Sect.D 58 441 11856829
1KH8 The crystal structure of the cis-proline to glycine variant (P114G) of ribonuclease A. Schultz, D.A., Friedman, A.M., White, M.A., Fox, R.O. 2005 Protein Sci. 14 2862 16199662
1KM8 The Structure of a Cytotoxic Ribonuclease From the Oocyte of Rana Catesbeiana (Bullfrog) Chern, S.-S., Musayev, F.N., Amiraslanov, I.R., Liao, Y.-D., Liaw, Y.-C. n/a To be Published n/a n/a n/a
1KM9 The Structure of a Cytotoxic Ribonuclease From the Oocyte of Rana Catesbeiana (Bullfrog) Chern, S.-S., Musayev, F.N., Amiraslanov, I.R., Liao, Y.-D., Liaw, Y.-C. n/a To be Published n/a n/a n/a
1KVZ Solution Structure of the Cytotoxic RNase 4 from the Oocytes of Bullfrog Rana Catesbeiana Hsu, C.-H., Liao, Y.-D., Pan, Y.-R., Chen, L.-W., Wu, S.-H., Leu, Y.-J., Chen, C. 2003 J.MOL.BIOL. 326 1189 12589762
1LSQ Deamidation in proteins: the crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67. Capasso, S., Di Donato, A., Esposito, L., Sica, F., Sorrentino, G., Vitagliano, L., Zagari, A., Mazzarella, L. 1996 J.Mol.Biol. 257 492 8648618
1M07 Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography Leu, Y.-J., Chern, S.-S., Wang, S.-C., Hsiao, Y.-Y., Amiraslanov, I., Liaw, Y.-C., Liao, Y.-D. 2003 J.Biol.Chem. 278 7300 12499382
1M58 1H, 15N and 13C resonance assignments and secondary structure determination of the RC-RNase 2 from oocytes of bullfrog Rana catesbeiana. Hsu, C.H., Chen, L.W., Liao, Y.D., Wu, S.H., Chen, C. 2001 J.Biomol.Nmr 19 87 11246862
1N0H Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase Pang, S.S., Guddat, L.W., Duggleby, R.G. 2003 J.BIOL.CHEM. 278 7639 14557277
1N1X The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative Sica, F., Di Fiore, A., Zagari, A., Mazzarella, L. 2003 Proteins: Struct., Funct., Genet. 52 263 12833549
1N3Z The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative Sica, F., Di Fiore, A., Zagari, A., Mazzarella, L. 2003 Proteins: Struct., Funct., Genet. 52 263 12833549
1NAK Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop. Stanfield, R.L., Ghiara, J.B., Ollmann Saphire, E., Profy, A.T., Wilson, I.A. 2003 Virology 315 159 14592768
1NKT Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase Sharma, V., Arockiasamy, A., Ronning, D.R., Savva, C.G., Holzenburg, A., Braunstein, M., Jacobs Jr., W.R., Sacchettini, J.C. 2003 Proc.Natl.Acad.Sci.USA 100 2243 12606717
1NL3 Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase Sharma, V., Arockiasamy, A., Ronning, D.R., Savva, C.G., Holzenburg, A., Braunstein, M., Jacobs Jr., W.R., Sacchettini, J.C. 2003 Proc.Natl.Acad.Sci.USA 100 2243 12606717
1O0F High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors Leonidas, D.D., Chavali, G.B., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M., Frankling, C., Acharya, K.R. 2003 PROTEIN SCI. 12 2559 14573867
1O0H High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors Leonidas, D.D., Chavali, G.B., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M., Frankling, C., Acharya, K.R. 2003 PROTEIN SCI. 12 2559 14573867
1O0M High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors Leonidas, D.D., Chavali, G.B., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M., Frankling, C., Acharya, K.R. 2003 PROTEIN SCI. 12 2559 14573867
1O0N High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors Leonidas, D.D., Chavali, G.B., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M., Frankling, C., Acharya, K.R. 2003 PROTEIN SCI. 12 2559 14573867
1O0O High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors Leonidas, D.D., Chavali, G.B., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M., Frankling, C., Acharya, K.R. 2003 PROTEIN SCI. 12 2559 14573867
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1QHC Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor. Leonidas, D.D., Shapiro, R., Irons, L.I., Russo, N., Acharya, K.R. 1999 Biochemistry 38 10287 10441122
1QMT Crystal structure of eosinophil cationic protein at 2.4 A resolution. Boix, E., Leonidas, D.D., Nikolovski, Z., Nogues, M.V., Cuchillo, C.M., Acharya, K.R. 1999 Biochemistry 38 16794 10606511
1QWQ THE SWAPPING OF TERMINAL ARMS IN RIBONUCLEASES: COMPARISON OF THE SOLUTION STRUCTURE OF MONOMERIC BOVINE SEMINAL AND PANCREATIC RIBONUCLEASES Avitabile, F., Alfano, C., Spadaccini, R., Crescenzi, O., D'Ursi, A.M., D'Alessio, G., Tancredi, T., Picone, D. 2003 Biochemistry 42 8704 12873130
1R3I The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates Zhou, Y., MacKinnon, R. 2003 J.Mol.Biol. 333 965 14583193
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1RAR Crystal structure of a fluorescent derivative of RNase A. Baudet-Nessler, S., Jullien, M., Crosio, M.P., Janin, J. 1993 Biochemistry 32 8457 8357795
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1RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
1RBB The crystal structure of ribonuclease B at 2.5-A resolution. Williams, R.L., Greene, S.M., McPherson, A. 1987 J.Biol.Chem. 262 16020 3680242
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1RHA Water-dependent domain motion and flexibility in ribonuclease A and the invariant features in its hydration shell. An X-ray study of two low-humidity crystal forms of the enzyme. Kishan, R.V., Chandra, N.R., Sudarsanakumar, C., Suguna, K., Vijayan, M. 1995 Acta Crystallogr.,Sect.D 51 703 15299799
1RHB Water-dependent domain motion and flexibility in ribonuclease A and the invariant features in its hydration shell. An X-ray study of two low-humidity crystal forms of the enzyme. Kishan, R.V., Chandra, N.R., Sudarsanakumar, C., Suguna, K., Vijayan, M. 1995 Acta Crystallogr.,Sect.D 51 703 15299799
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1RNF The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity. Terzyan, S.S., Peracaula, R., de Llorens, R., Tsushima, Y., Yamada, H., Seno, M., Gomis-Ruth, F.X., Coll, M. 1999 J.Mol.Biol. 285 205 9878400
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1RNN Structure of the Crystalline Complex of Bovine Pancreatic Ribonuclease A and Cytidylic Acid Fedorov, A.A., Josef-Mccarthy, D., Graf, I., Anguelova, D., Fedorov, E.V., Almo, S.C. n/a To be Published n/a n/a n/a
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1RNU Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures. Kim, E.E., Varadarajan, R., Wyckoff, H.W., Richards, F.M. 1992 Biochemistry 31 12304 1463719
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1T9A Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. McCourt, J.A., Pang, S.S., Guddat, L.W., Duggleby, R.G. 2005 Biochemistry 44 2330 15709745
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1TQ9 Structure and Stability of the Non-covalent Swapped Dimer of Bovine Seminal Ribonuclease: AN ENZYME TAILORED TO EVADE RIBONUCLEASE PROTEIN INHIBITOR Sica, F., Di Fiore, A., Merlino, A., Mazzarella, L. 2004 J.Biol.Chem. 279 36753 15192098
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1UN4 Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41. Holloway, D.E., Chavali, G.B., Hares, M.C., Baker, M.D., Subbarao, G.V., Shapiro, R., Acharya, K.R. 2004 Biochemistry 43 1230 14756559
1UN5 Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41. Holloway, D.E., Chavali, G.B., Hares, M.C., Baker, M.D., Subbarao, G.V., Shapiro, R., Acharya, K.R. 2004 Biochemistry 43 1230 14756559
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1Y92 The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE. Picone, D., Di Fiore, A., Ercole, C., Franzese, M., Sica, F., Tomaselli, S., Mazzarella, L. 2005 J.Biol.Chem. 280 13771 15647261
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1YV4 The Importance of Dynamic Effects on the Enzyme Activity: X-RAY STRUCTURE AND MOLECULAR DYNAMICS OF ONCONASE MUTANTS Merlino, A., Mazzarella, L., Carannante, A., Di Fiore, A., Di Donato, A., Notomista, E., Sica, F. 2005 J.Biol.Chem. 280 17953 15728177
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2ATK Molecular determinants of gating at the potassium-channel selectivity filter. Cordero-Morales, J.F., Cuello, L.G., Zhao, Y., Jogini, V., Cortes, D.M., Roux, B., Perozo, E. 2006 Nat.Struct.Mol.Biol. 13 311 16532009
2BEX Molecular recognition of human eosinophil-derived neurotoxin (RNase 2) by placental ribonuclease inhibitor. Iyer, S., Holloway, D.E., Kumar, K., Shapiro, R., Acharya, K.R. 2005 J.Mol.Biol. 347 637 15755456
2BLP Improving radiation-damage substructures for RIP. Nanao, M.H., Sheldrick, G.M., Ravelli, R.B. 2005 Acta Crystallogr.,Sect.D 61 1227 16131756
2BLZ Improving radiation-damage substructures for RIP. Nanao, M.H., Sheldrick, G.M., Ravelli, R.B. 2005 Acta Crystallogr.,Sect.D 61 1227 16131756
2BOB Structural basis of TEA blockade in a model potassium channel. Lenaeus, M.J., Vamvouka, M., Focia, P.J., Gross, A. 2005 Nat.Struct.Mol.Biol. 12 454 15852022
2BOC Structural basis of TEA blockade in a model potassium channel. Lenaeus, M.J., Vamvouka, M., Focia, P.J., Gross, A. 2005 Nat.Struct.Mol.Biol. 12 454 15852022
2BWK Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies. Holloway, D.E., Chavali, G.B., Hares, M.C., Subramanian, V., Acharya, K.R. 2005 Acta Crystallogr.,Sect.D 61 1568 16301790
2BWL Structure of murine angiogenin: features of the substrate- and cell-binding regions and prospects for inhibitor-binding studies. Holloway, D.E., Chavali, G.B., Hares, M.C., Subramanian, V., Acharya, K.R. 2005 Acta Crystallogr.,Sect.D 61 1568 16301790
2BZZ Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A. Baker, M.D., Holloway, D.E., Swaminathan, G.J., Acharya, K.R. 2006 Biochemistry 45 416 16401072
2C01 Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A. Baker, M.D., Holloway, D.E., Swaminathan, G.J., Acharya, K.R. 2006 Biochemistry 45 416 16401072
2C02 Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A. Baker, M.D., Holloway, D.E., Swaminathan, G.J., Acharya, K.R. 2006 Biochemistry 45 416 16401072
2C05 Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A. Baker, M.D., Holloway, D.E., Swaminathan, G.J., Acharya, K.R. 2006 Biochemistry 45 416 16401072
2DGA Molecular and Structural Characterization of Hexameric beta-D-Glucosidases in Wheat and Rye. Sue, M., Yamazaki, K., Yajima, S., Nomura, T., Matsukawa, T., Iwamura, H., Miyamoto, T. 2006 Plant Physiol. 141 1237 16751439
2DWD Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel Yohannan, S., Hu, Y., Zhou, Y. 2007 J.Mol.Biol. 366 806 17196615
2DWE Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel Yohannan, S., Hu, Y., Zhou, Y. 2007 J.Mol.Biol. 366 806 17196615
2E0J 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines Yamada, H., Tamada, T., Kosaka, M., Miyata, K., Fujiki, S., Tano, M., Moriya, M., Yamanishi, M., Honjo, E., Tada, H., Ino, T., Yamaguchi, H., Futami, J., Seno, M., Nomoto, T., Hirata, T., Yoshimura, M., Kuroki, R. 2007 Protein Sci. 16 1389 17586772
2E0L 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines Yamada, H., Tamada, T., Kosaka, M., Miyata, K., Fujiki, S., Tano, M., Moriya, M., Yamanishi, M., Honjo, E., Tada, H., Ino, T., Yamaguchi, H., Futami, J., Seno, M., Nomoto, T., Hirata, T., Yoshimura, M., Kuroki, R. 2007 Protein Sci. 16 1389 17586772
2E0M 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines Yamada, H., Tamada, T., Kosaka, M., Miyata, K., Fujiki, S., Tano, M., Moriya, M., Yamanishi, M., Honjo, E., Tada, H., Ino, T., Yamaguchi, H., Futami, J., Seno, M., Nomoto, T., Hirata, T., Yoshimura, M., Kuroki, R. 2007 Protein Sci. 16 1389 17586772
2E0O 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines Yamada, H., Tamada, T., Kosaka, M., Miyata, K., Fujiki, S., Tano, M., Moriya, M., Yamanishi, M., Honjo, E., Tada, H., Ino, T., Yamaguchi, H., Futami, J., Seno, M., Nomoto, T., Hirata, T., Yoshimura, M., Kuroki, R. 2007 Protein Sci. 16 1389 17586772
2E33 Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase Mizushima, T., Yoshida, Y., Kumanomidou, T., Hasegawa, Y., Suzuki, A., Yamane, T., Tanaka, K. 2007 Proc.Natl.Acad.Sci.Usa 104 5777 17389369
2E3W Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A Boerema, D.J., Tereshko, V.A., Kent, S.B. 2008 Biopolymers 90 278 17610259
2F3L Characterization of two potentially universal turn motifs that shape the repeated five-residues fold-Crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142. Buchko, G.W., Ni, S., Robinson, H., Welsh, E.A., Pakrasi, H.B., Kennedy, M.A. 2006 Protein Sci. 15 2579 17075135
2F58 Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Stanfield, R., Cabezas, E., Satterthwait, A., Stura, E., Profy, A., Wilson, I. 1999 Structure Fold.Des. 7 131 10368281
2G0Y Characterization of two potentially universal turn motifs that shape the repeated five-residues fold - Crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142 Buchko, G.W., Ni, S., Robinson, H., Welsh, E.A., Pakrasi, H.B., Kennedy, M.A. 2006 Protein Sci. 15 2579 17075135
2G4W On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Mueller-Dieckmann, C., Panjikar, S., Schmidt, A., Mueller, S., Kuper, J., Geerlof, A., Wilmanns, M., Singh, R.K., Tucker, P.A., Weiss, M.S. 2007 Acta Crystallogr.,Sect.D 63 366 17327674
2G4X On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Mueller-Dieckmann, C., Panjikar, S., Schmidt, A., Mueller, S., Kuper, J., Geerlof, A., Wilmanns, M., Singh, R.K., Tucker, P.A., Weiss, M.S. 2007 Acta Crystallogr.,Sect.D 63 366 17327674
2G8Q The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal. Leonidas, D.D., Maiti, T.K., Samanta, A., Dasgupta, S., Pathak, T., Zographos, S.E., Oikonomakos, N.G. 2006 Bioorg.Med.Chem. 14 6055 16730994
2G8R The binding of 3'-N-piperidine-4-carboxyl-3'-deoxy-ara-uridine to ribonuclease A in the crystal. Leonidas, D.D., Maiti, T.K., Samanta, A., Dasgupta, S., Pathak, T., Zographos, S.E., Oikonomakos, N.G. 2006 Bioorg.Med.Chem. 14 6055 16730994
2GMK Structural basis for catalysis by onconase. Lee, J.E., Bae, E., Bingman, C.A., Phillips Jr., G.N., Raines, R.T. 2008 J.Mol.Biol. 375 165 18001769
2H8P Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. Valiyaveetil, F.I., Sekedat, M., Mackinnon, R., Muir, T.W. 2006 J.Am.Chem.Soc. 128 11591 16939283
2HFE Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. Valiyaveetil, F.I., Sekedat, M., Mackinnon, R., Muir, T.W. 2006 J.Am.Chem.Soc. 128 11591 16939283
2HG5 Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. Valiyaveetil, F.I., Sekedat, M., Mackinnon, R., Muir, T.W. 2006 J.Am.Chem.Soc. 128 11591 16939283
2HJF Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations. Faraldo-Gomez, J.D., Kutluay, E., Jogini, V., Zhao, Y., Heginbotham, L., Roux, B. 2007 J.Mol.Biol. 365 649 17070844
2HKY The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity. Huang, Y.C., Lin, Y.M., Chang, T.W., Wu, S.J., Lee, Y.S., Chang, M.D., Chen, C., Wu, S.H., Liao, Y.D. 2007 J.Biol.Chem. 282 4626 17150966
2HVJ Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. Yohannan, S., Hu, Y., Zhou, Y. 2007 J.Mol.Biol. 366 806 17196615
2HVK Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. Yohannan, S., Hu, Y., Zhou, Y. 2007 J.Mol.Biol. 366 806 17196615
2I5S Structural basis for catalysis by onconase. Lee, J.E., Bae, E., Bingman, C.A., Phillips Jr., G.N., Raines, R.T. 2008 J.Mol.Biol. 375 165 18001769
2IH1 Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Valiyaveetil, F.I., Leonetti, M., Muir, T.W., Mackinnon, R. 2006 Science 314 1004 17095703
2IH3 Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Valiyaveetil, F.I., Leonetti, M., Muir, T.W., Mackinnon, R. 2006 Science 314 1004 17095703
2ITC Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Lockless, S.W., Zhou, M., Mackinnon, R. 2007 Plos Biol. 5 e121 17472437
2ITD Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Lockless, S.W., Zhou, M., Mackinnon, R. 2007 Plos Biol. 5 e121 17472437
2J4T Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein Crabtree, B., Holloway, D.E., Baker, M.D., Acharya, K.R., Subramanian, V. 2007 Biochemistry 46 2431 n/a
2JNC Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand Grace, C.R.R., Perrin, M.H., Jozsef, G., DiGruccio, M.R., Cantle, J.P., Rivier, J.E., Vale, W.W., Riek, R. 2007 Proc.Natl.Acad.Sci.USA 104 4858 17360332
2JND Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand Grace, C.R.R., Perrin, M.H., Jozsef, G., DiGruccio, M.R., Cantle, J.P., Rivier, J.E., Vale, W.W., Riek, R. 2007 Proc.Natl.Acad.Sci.USA 104 4858 17360332
2K11 The solution structure and dynamics of human pancreatic ribonuclease determined by NMR spectroscopy provide insight into its remarkable biological activities and inhibition. Kover, K.E., Bruix, M., Santoro, J., Batta, G., Laurents, D.V., Rico, M. 2008 J.Mol.Biol. 379 953 18495155
2NLJ Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Lockless, S.W., Zhou, M., Mackinnon, R. 2007 Plos Biol. 5 e121 17472437
2NUI Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A Boerema, D.J., Tereshko, V.A., Kent, S.B. 2008 Biopolymers 90 278 17610259
2OP2 Implementation of a k/k(0) Method to Identify Long-Range Structure in Transition States during Conformational Folding/Unfolding of Proteins. Pradeep, L., Kurinov, I., Ealick, S.E., Scheraga, H.A. 2007 Structure 15 1178 17937908
2OQF Design, Synthesis, and Characterization of Non-natural RNase A Analogues with Enhanced Second-step Catalytic Activity Boerema, D.J., Tereshko, V.A., Zhang, J.L., He, C., Kent, S.B.H. n/a To be Published n/a n/a n/a
2P42 Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. 2008 Protein Sci. 17 1175 18445622
2P43 Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. 2008 Protein Sci. 17 1175 18445622
2P44 Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. 2008 Protein Sci. 17 1175 18445622
2P45 Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. 2008 Protein Sci. 17 1175 18445622
2P46 Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. 2008 Protein Sci. 17 1175 18445622
2P47 Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. 2008 Protein Sci. 17 1175 18445622
2P48 Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. 2008 Protein Sci. 17 1175 18445622
2P49 Exploring the affinity limit of single-domain antibody mimics: affinity maturation to picomolar KD of a VHH with a flat paratope comprising only two surface loops Koide, A., Tereshko, V., Uysal, S., Margalef, K., Kossiakoff, A.A., Koide, S. n/a To be Published n/a n/a n/a
2P4A Exploring the affinity limit of single-domain antibody mimics: affinity maturation to picomolar KD of a VHH with a flat paratope comprising only two surface loops Koide, A., Tereshko, V., Uysal, S., Margalef, K., Kossiakoff, A.A., Koide, S. n/a To be Published n/a n/a n/a
2P6Z Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes. Singh, U.P., Ardelt, W., Saxena, S.K., Holloway, D.E., Vidunas, E., Lee, H.S., Saxena, A., Shogen, K., Acharya, K.R. 2007 J.Mol.Biol. 371 93 17560606
2P7S Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes. Singh, U.P., Ardelt, W., Saxena, S.K., Holloway, D.E., Vidunas, E., Lee, H.S., Saxena, A., Shogen, K., Acharya, K.R. 2007 J.Mol.Biol. 371 93 17560606
2P7T Crystal Structure of KcsA mutant Cordero-Morales, J.F., Vishwanath, J., Lewis, A., Vasquez, V., Cortes, D.M., Roux, B., Perozo, E. n/a To be Published n/a n/a n/a
2Q4G Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. Johnson, R.J., McCoy, J.G., Bingman, C.A., Phillips Jr., G.N., Raines, R.T. 2007 J.Mol.Biol. 368 434 17350650
2QCA A new crystal form of bovine pancreatic RNase A in complex with 2'-deoxyguanosine-5'-monophosphate. Larson, S.B., Day, J.S., Cudney, R., McPherson, A. 2007 Acta Crystallogr.,Sect.F 63 728 17768339
2RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
2RLN Thermodynamic and structural consequences of changing a sulfur atom to a methylene group in the M13Nle mutation in ribonuclease-S. Thomson, J., Ratnaparkhi, G.S., Varadarajan, R., Sturtevant, J.M., Richards, F.M. 1994 Biochemistry 33 8587 8031793
2RNF The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity. Terzyan, S.S., Peracaula, R., de Llorens, R., Tsushima, Y., Yamada, H., Seno, M., Gomis-Ruth, F.X., Coll, M. 1999 J.Mol.Biol. 285 205 9878400
2RNS Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures. Kim, E.E., Varadarajan, R., Wyckoff, H.W., Richards, F.M. 1992 Biochemistry 31 12304 1463719
2VQ8 Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and Their Evolutionary Implications Kazakou, K., Holloway, D.E., Prior, S.H., Subramanian, V., Acharya, K.R. 2008 J.Mol.Biol. 380 206 18508078
2VQ9 Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and Their Evolutionary Implications Kazakou, K., Holloway, D.E., Prior, S.H., Subramanian, V., Acharya, K.R. 2008 J.Mol.Biol. 380 206 18508078
2Z91 How Protein Recognizes Ladder-like Polycyclic Ethers: INTERACTIONS BETWEEN CIGUATOXIN (CTX3C) FRAGMENTS AND ITS SPECIFIC ANTIBODY 10C9 Ui, M., Tanaka, Y., Tsumuraya, T., Fujii, I., Inoue, M., Hirama, M., Tsumoto, K. 2008 J.Biol.Chem. 283 19440 18463096
2Z92 How Protein Recognizes Ladder-like Polycyclic Ethers: INTERACTIONS BETWEEN CIGUATOXIN (CTX3C) FRAGMENTS AND ITS SPECIFIC ANTIBODY 10C9 Ui, M., Tanaka, Y., Tsumuraya, T., Fujii, I., Inoue, M., Hirama, M., Tsumoto, K. 2008 J.Biol.Chem. 283 19440 18463096
2Z93 How Protein Recognizes Ladder-like Polycyclic Ethers: INTERACTIONS BETWEEN CIGUATOXIN (CTX3C) FRAGMENTS AND ITS SPECIFIC ANTIBODY 10C9 Ui, M., Tanaka, Y., Tsumuraya, T., Fujii, I., Inoue, M., Hirama, M., Tsumoto, K. 2008 J.Biol.Chem. 283 19440 18463096
2ZMC Crystal Structure of the Catalytic Domain of the Mitotic Checkpoint Kinase Mps1 in Complex with SP600125 Chu, M.L., Chavas, L.M., Douglas, K.T., Eyers, P.A., Tabernero, L. 2008 J.Biol.Chem. 283 21495 18480048
2ZMD Crystal Structure of the Catalytic Domain of the Mitotic Checkpoint Kinase Mps1 in Complex with SP600125 Chu, M.L., Chavas, L.M., Douglas, K.T., Eyers, P.A., Tabernero, L. 2008 J.Biol.Chem. 283 21495 18480048
2ZPO Crystal Structure of Newly Found Green Turtle Egg White Ribonuclease Katekaew, S., Kakuta, Y., Torikata, T., Kimura, M., Yoneda, K., Araki, T. n/a To be Published n/a n/a n/a
3BCM The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme Merlino, A., Ercole, C., Picone, D., Pizzo, E., Mazzarella, L., Sica, F. 2008 J.Mol.Biol. 376 427 18164315
3BCO The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme Merlino, A., Ercole, C., Picone, D., Pizzo, E., Mazzarella, L., Sica, F. 2008 J.Mol.Biol. 376 427 18164315
3BCP The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme Merlino, A., Ercole, C., Picone, D., Pizzo, E., Mazzarella, L., Sica, F. 2008 J.Mol.Biol. 376 427 18164315
3D9A High Resolution Crystal Structure Structure of HyHel10 Fab Complexed to Hen Egg Lysozyme Acchione, M., DeSantis, M., Shanmuganathan, A., Lipshcultz, C., Smith-Gill, S. n/a TO BE PUBLISHED n/a n/a n/a
3DH5 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Kurpiewska, K., Font, J., Ribo, M., Vilanova, M., Lewinski, K. n/a To be Published n/a n/a n/a
3DH6 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Kurpiewska, K., Font, J., Ribo, M., Vilanova, M., Lewinski, K. n/a To be Published n/a n/a n/a
3DI7 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Kurpiewska, K., Font, J., Ribo, M., Vilanova, M., Lewinski, K. n/a To be Published n/a n/a n/a
3DI8 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Kurpiewska, K., Font, J., Ribo, M., Vilanova, M., Lewinski, K. n/a To be Published n/a n/a n/a
3DI9 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Kurpiewska, K., Font, J., Ribo, M., Vilanova, M., Lewinski, K. n/a To be Published n/a n/a n/a
3DIB X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Kurpiewska, K., Font, J., Ribo, M., Vilanova, M., Lewinski, K. n/a To be Published n/a n/a n/a
3DIC X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Kurpiewska, K., Font, J., Ribo, M., Vilanova, M., Lewinski, K. n/a To be Published n/a n/a n/a
3DO9 Crystal Structure of Protein Ba1542 from Bacillus Anthracis Str.Ames. Patskovsky, Y., Ozyurt, S., Freeman, J., Iizuka, M., Maletic, M., Smith, D., Wasserman, S., Sauder, J.M., Burley, S.K., Almo, S.C. n/a To be Published n/a n/a n/a
3E46 The High Resolution Crystal Structure of Ubiquitin-Conjugating Enzyme E2-25kDa (Huntington Interacting Protein 2) M172A Mutant. Wilson, R.C., Hughes, R.C., Flatt, J.W., Meehan, E.J., Ng, J.D., Twigg, P.D. n/a to be published n/a n/a n/a
3F58 Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Stanfield, R., Cabezas, E., Satterthwait, A., Stura, E., Profy, A., Wilson, I. 1999 Structure Fold.Des. 7 131 10368281
3HFM Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex. Padlan, E.A., Silverton, E.W., Sheriff, S., Cohen, G.H., Smith-Gill, S.J., Davies, D.R. 1989 Proc.Natl.Acad.Sci.USA 86 5938 2762305
3RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
3RN3 Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model. Howlin, B., Moss, D.S., Harris, G.W. 1989 Acta Crystallogr., Sect.A 45 851 2619965
3RSD His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes. Schultz, L.W., Quirk, D.J., Raines, R.T. 1998 Biochemistry 37 8886 9636030
3RSK Coulombic Effects of Remote Subsites on the Active Site of Ribonuclease A Fisher, B.M., Schultz, L.W., Raines, R.T. 1998 Biochemistry 37 17386 9860854
3RSP Structure and stability of the P93G variant of ribonuclease A. Schultz, L.W., Hargraves, S.R., Klink, T.A., Raines, R.T. 1998 Protein Sci. 7 1620 9684895
3SRN Structural changes that accompany the reduced catalytic efficiency of two semisynthetic ribonuclease analogs. deMel, V.S., Martin, P.D., Doscher, M.S., Edwards, B.F. 1992 J.Biol.Chem. 267 247 1730593
4RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
4RSD His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes. Schultz, L.W., Quirk, D.J., Raines, R.T. 1998 Biochemistry 37 8886 9636030
4RSK Coulombic Effects of Remote Subsites on the Active Site of Ribonuclease A Fisher, B.M., Schultz, L.W., Raines, R.T. 1998 Biochemistry 37 17386 9860854
4SRN Structural changes that accompany the reduced catalytic efficiency of two semisynthetic ribonuclease analogs. deMel, V.S., Martin, P.D., Doscher, M.S., Edwards, B.F. 1992 J.Biol.Chem. 267 247 1730593
5RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
6RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
6RSA Nuclear magnetic resonance and neutron diffraction studies of the complex of ribonuclease A with uridine vanadate, a transition-state analogue. Borah, B., Chen, C.W., Egan, W., Miller, M., Wlodawer, A., Cohen, J.S. 1985 Biochemistry 24 2058 4016100
7RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
7RSA Structure of phosphate-free ribonuclease A refined at 1.26 A. Wlodawer, A., Svensson, L.A., Sjolin, L., Gilliland, G.L. 1988 Biochemistry 27 2705 3401445
8RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
8RSA Crystal structure of two covalent nucleoside derivatives of ribonuclease A. Nachman, J., Miller, M., Gilliland, G.L., Carty, R., Pincus, M., Wlodawer, A. 1990 Biochemistry 29 928 2340284
9RAT Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K. Tilton Jr., R.F., Dewan, J.C., Petsko, G.A. 1992 Biochemistry 31 2469 1547232
9RSA Crystal structure of two covalent nucleoside derivatives of ribonuclease A. Nachman, J., Miller, M., Gilliland, G.L., Carty, R., Pincus, M., Wlodawer, A. 1990 Biochemistry 29 928 2340284



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